Backend With Ionic?

Can I use Prisma, Graphql, nexus, and Apollo with ionic/react? Im trying to create a backend with these tools

Ionic apps typically communicate with backends using HTTP/REST, so there are no constraints on the actual implementation language / framework / libraries used in the backend. If you can make something that speaks HTTP, and pick a domain transfer language (JSON is far and away the most typical), you’re good to go.