Android 6.0.1 apk not responding problem

Hi,
I have webapp with a ionic framework.
Now I can run debug version on 6.0.1.Everything is ok.
But when start apk with release version on 6.0.1,display " XXX isn’t responding,do you want to close it?"
How to solve it.
Thanks.

App have ant problem.I update my plugin then solve it.