Changing Ionic SCSS Variables

For example: /src/components/item/
font-size: $item-md-font-size;

how can I change the value? I tried appending the variables.scss file:
$item-md-font-size: 32px;

But it doesn’t work. The value remains at 16px.
(There is no CSS variable for the font-size. only SASS variables)

It uses CSS Shadow Parts so you have to do this:

ion-item::part(native) {
    font-size: 32px;